Transforming Tubulin Therapy for Brain Diseases
Breaking through the blood-brain barrier with breakthrough treatment.
The BBB is a constant hurdle for brain tumor treatments.
Reglagene is developing a tubulin-targeting therapy that is orally administered, well-tolerated, and blood-brain barrier penetrant for the treatment of brain cancers.
Our tubulin-targeted therapy redefines brain cancer treatment.
Passively crosses blood-brain barrier using small-molecule therapy.
Half the size of the FDA-approved tubulin targeting therapies, our therapy has low molecular weight which makes it easier to pass into cells and into the brain.
84% tumor growth reduction relative to placebo and Standard of Care temozolomide.
In animal efficacy studies (mice) Reglagene’s medicine works where Standard of Care fails.
Stays in the brain to kill cancer.
Efflux pumps sit in the brain and remove toxins (or medicines). Reglagene’s medicine is not recognized by efflux pumps. It stays in the brain and keeps attacking the tumor.
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